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Clinical Studies and Other Research

Clinical trials are an important way for medical researchers to expand existing knowledge, so that medical care can improve in the future. Whether or not to participte in clinical studies is an important individual decision that should be based on careful review of each study and discussion with your personal physician.

Researchers: let us know about studies for which you are recruiting.

Below are studies in our area that are currently seeking participants.
Additional information will be added to this page as it becomes available.


Infant Study
Food allergy is a frequent problem in young children. It has become more and more common in the past decades. Boston Children’s Hospital is conducting a study to see if there are differences between children who have food allergies and children who do not. Specifically, they would like to know if children with food allergies have differences in their digestive system.
Everyone has bacteria in their gastrointestinal tract that are an important part of a healthy digestive system. This study examines whether children with food allergies have different species of bacteria than children without food allergies.

Participation includes:
• Providing up to 9 of your child’s stool samples (Children’s Hospital will pick them up from your house)
• Completing a survey about your child’s medical history and your own health with each sample
Eligibility criteria:
• 1 week of age to 15 months of age at first collection
• Healthy with no food allergies or have food allergies
• Have never taken immunosuppressive drugs

Compensation will be provided for each collection

For more information or to enroll your child, contact William Secor at 617-355-4874 or William.Secor@childrens.harvard.edu.

Atopic Dermatitis Research Network
After May, 2015: not currently seeking new participants.
Click here for information about this study and who to contact about possible future studies that include people with eczema

Does Your Child Wheeze or Have Asthma?
(multiple studies being conducted involving children ages 1-17)
Click here for more information

New “app” for asthma patients:
Designed to improve information sharing between patients and healthcare providers and identify potential problems between office visits.
Note: This is currently available as part of a trial only by patients of Boston Children’s Hospital, Martha Eliot Health Center, or Primary Care at Longwood.

“TriVox Health is an online tool used for monitoring chronic diseases, such as asthma. TriVox sends monthly surveys to be completed by the patient (if old enough), the parents, and even a school nurse, if applicable. The healthcare provider that manages the patient’s asthma care is then able to see the results from month to month to gain a better sense of how well the patient’s asthma is being managed. TriVox is being used at Boston Children’s Hospital in multiple clinics for six diseases, and surveys can be completed via web browser or a mobile app.

If you or your child are followed for your asthma at Boston Children’s Hospital, Martha Eliot Health Center, or Primary Care at Longwood, ask them if they are using TriVox and get signed up!”
For additional information, contact William Secor at 617-919-4115 or William.Secor@childrens.harvard.edu

The Brigham and Women’s Asthma Research Center is currently conducting a study looking at using an FDA-approved medication, not previously used for asthma, to treat severe asthma.

If you are between the ages of 18-65 and you still have asthma symptoms despite using at least Advair, Symbicort, or Dulera (you can be using other medications in addition to these as well), you may be eligible for this new study.

The drug targets mast cells that we believe play a role in asthma.  You will be seen by a Brigham and Women’s asthma physician and you will receive the study medication or placebo (a sugar pill that contains no active medication) at no cost. We will evaluate your breathing tests, symptoms, allergy skin tests, and evaluate your airways by performing a bronchoscopy. Your current asthma medications will not be changed, but we will ask you to withhold them at certain times. We will follow you closely for 7 months (18 visits). You will be compensated $2000 for your time while participating in the study and transportation costs.

If you are interested in learning more about this study, or others,  please call 617-732-8201 or 1-888-99-ASTHMA.

Click here for descriptions of other clinical trials.

The Brigham and Women’s Asthma Research Center is dedicated to studying new ways to treat asthma and help people breathe easier.



These clinical trials and research studies are currently seeking participants:

– Peanut allergy (ages 7-55 years): “Clinical Desensitization and Tolerance Following Peanut Oral Immunotherapy and Subsequent Allergen Avoidance”
click here for a flyer or call 617-643-5952 or e-mail: foodallergy@mgh.harvard.edu

– “Biomarkers of Tolerance in Pediatric Milk Allergy”
Click here for additional details  or call 617-726-3850.

If you are interested in hearing about research trials at MGH as they become available send an email to foodallergy@mgh.harvard.edu.


Rhode Island Hospital/Hasbro Children’s Hospital

Children between 8-12 years old with food allergies and their caregivers are invited to participate in a project to learn more about living safely with food allergies. This is a study of how technology, specifically a computer program or “App,” named Food Allergy Adventure can be useful in educating children and their families about their food allergies.

Click here for a flyer with more information


Additional information will be added to this page as it becomes available.